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Upper Abdominal Pain, Alert To Acute Pancreatitis

2025-9-2


The recently concluded quadrennial World Cup should be a carnival for many football fans, as they watch intense matches late at night and also order a late night snack to cheer them up. And there is a part of this group of people who suddenly feel extremely severe pain in their upper abdomen. They don't know what specific disease it is, and only when they call the emergency department did they learn from the medical staff that they have sudden acute pancreatitis and need emergency treatment.

Pancreatitis is not a very common disease type in daily life, which leads to limited understanding of pancreatitis among people. So, today the editor will talk about some medical knowledge about pancreatitis, hoping that everyone can have a more comprehensive and in-depth understanding of this disease, so as to ensure their own health.

1、 Cause of onset

1. Factors related to biliary system diseases. The most common diseases of the biliary system in the body are gallstones and biliary inflammation, which can easily trigger this disease.

2. Alcohol factor. According to relevant studies, alcohol can affect the protein content in the human body, leading to the formation of protein "plugs" and ultimately causing pancreatic duct obstruction, resulting in inflammation of the pancreas. In addition, alcohol can also stimulate the duodenal mucosa, thereby affecting the normal discharge of pancreatic juice.

3. Vascular factors. Acute thrombosis and vascular obstruction in pancreatic arterioles, veins, etc. can also lead to the occurrence of this disease. There is also a situation where pancreatic duct obstruction leads to an increase in pancreatic duct pressure, and pancreatic enzymes stimulate blood vessels, lymph nodes, etc. in the interstitium, ultimately leading to tissue necrosis.

4. Infection factors. The disease may also occur due to bacterial or viral invasion of pancreatic tissue.

5. Other factors such as metabolic diseases, drug allergies, etc. can also cause acute pancreatitis.

2、 Clinical characteristics

1. Mild abdominal pain, prone to misdiagnosis. People may experience persistent pain in their upper abdomen after meals. At this time, it is important to go to a regular hospital for blood or urine amylase testing as early as possible, which can help medical personnel diagnose. Generally, blood amylase levels begin to increase at 6 hours of onset and reach their peak within 8-12 hours. This abnormal value can last for 48-72 hours.

2. Some people may not have obvious pain areas in pancreatitis, and some may feel pain in the chest or lower abdomen, which can easily lead to misdiagnosis by medical personnel.

3. The hemorrhagic necrotic type of this disease is more common in the elderly population. The upper and middle abdomen of the elderly will feel very obvious pain, especially when pressed. This pain can also affect multiple organs in the body, leading to clinical symptoms such as shock, toxic myocarditis, and acute kidney failure in the elderly.

4. The etiology is complex. In addition to the above characteristics, acute pancreatitis also carries the risk of pancreatic ischemia. Once suspected or diagnosed with this disease, hospitalization procedures should be promptly completed for diagnosis and treatment.

5. Repeated occurrences. Generally speaking, the disease can recover after symptomatic treatment and active and effective treatment such as removing the cause. However, in clinical practice, some patients often complain that their dietary habits are already very particular and they do not have problems such as gallstones, but they always "suddenly" develop acute pancreatitis unintentionally, which greatly affects their quality of daily life. This is mostly due to the repeated acute attacks of the disease, and at this time, people often experience changes in pancreatic function and structure, such as pancreatic calcification and irregular twisting of the pancreatic duct.

3、 Most cases of acute pancreatitis are mild and can be cured with appropriate internal medicine treatment. But some of them can develop into heavy ones with extremely high danger. For the diagnosis and treatment of acute pancreatitis, long-term intensive care treatment is required. At present, there is no targeted drug therapy in clinical practice. The main treatment plan in clinical practice is supportive therapy that delivers drugs while also providing anti-inflammatory and analgesic effects. However, this plan requires a high level of restorative function from the patient's own body. In addition, in actual clinical treatment, medical personnel will combine the patient's actual condition to determine whether to administer conservative treatment with intravenous nutrient solution or use surgical endoscopic treatment.

Finally, if you still want to prevent this disease, you need to control your diet, achieve a reasonable combination of meat and vegetables, be light and low in oil, avoid overeating for dinner, and avoid eating late night snacks and drinking alcohol. Timely treatment of biliary diseases and avoidance of overeating to reduce pancreatic burden.